HBV Target gene Detail Information

> CDC73 Gene Search Result

Gene Information

Gene Name	CDC73
Gene ID	79577
Gene Full Name	cell division cycle 73
Gene Alias	HYX; FIHP; HPTJT; HRPT1; HRPT2; C1orf28
Transcripts	ENSG00000134371
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q6P1J9
HGNC ID	HGNC:16783
VEGA ID	OTTHUMG00000035676
OMIM ID	607393
String ID	9606.ENSP00000356405
PharmGKB ID	PA29464

Target gene [CDC73] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009752	chr1	14			14	View
1402320	chr1	14			14	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CDC73 expression and immune infiltrating cell level correlation result in HBV+ samples
CDC73 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).