HIV Target gene Detail Information

> CDC45 Gene Search Result

Gene Information

Gene Name	CDC45
Gene ID	8318
Gene Full Name	cell division cycle 45
Gene Alias	CDC45L; MGORS7; CDC45L2; PORC-PI-1
Transcripts	ENSG00000093009
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Centrosome;Cytosol;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	O75419
HGNC ID	HGNC:1739
VEGA ID	OTTHUMG00000150386
OMIM ID	603465
String ID	9606.ENSP00000405726
PharmGKB ID	PA371

Target gene [CDC45] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4012483	chr22	2	3		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CDC45 expression and immune infiltrating cell level correlation result in HIV+ samples
CDC45 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).