HIV Target gene Detail Information

> CDC42SE2 Gene Search Result

Gene Information

Gene Name	CDC42SE2
Gene ID	56990
Gene Full Name	CDC42 small effector 2
Gene Alias	SPEC2
Transcripts	ENSG00000158985
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9NRR3
HGNC ID	HGNC:18547
VEGA ID	OTTHUMG00000162692
String ID	9606.ENSP00000427421
PharmGKB ID	PA133787056

Target gene [CDC42SE2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000536	chr5	44	209	136	389	View
4003956	chr5	52			52	View
4004664	chr5	38	2	1	41	View
4007575	chr5	17	2		19	View
4009699	chr5	11			11	View
4009852	chr5	10			10	View
4010507	chr5	7	2		9	View
4016530	chr5				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CDC42SE2 expression and immune infiltrating cell level correlation result in HIV+ samples
CDC42SE2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CDC42SE2 expression and immune infiltrating cell level correlation result in HIV+ samples
CDC42SE2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).