HIV Target gene Detail Information

> CDC42EP3 Gene Search Result

Gene Information

Gene Name	CDC42EP3
Gene ID	10602
Gene Full Name	CDC42 effector protein 3
Gene Alias	UB1; CEP3; BORG2
Transcripts	ENSG00000163171
Virus	HIV
Gene Type	protein coding
HPA Location Info	Actin filaments;Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9UKI2
HGNC ID	HGNC:16943
VEGA ID	OTTHUMG00000100971
OMIM ID	606133
String ID	9606.ENSP00000295324
PharmGKB ID	PA38429

Target gene [CDC42EP3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000757	chr2	137	33	120	290	View
4001402	chr2	93	27	49	169	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CDC42EP3 expression and immune infiltrating cell level correlation result in HIV+ samples
CDC42EP3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CDC42EP3 expression and immune infiltrating cell level correlation result in HIV+ samples
CDC42EP3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).