HIV Target gene Detail Information

> CDC42BPB Gene Search Result

Gene Information

Gene Name	CDC42BPB
Gene ID	9578
Gene Full Name	CDC42 binding protein kinase beta
Gene Alias	MRCKB
Transcripts	ENSG00000198752
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q9Y5S2
HGNC ID	HGNC:1738
VEGA ID	OTTHUMG00000171898
OMIM ID	614062
String ID	9606.ENSP00000355237
PharmGKB ID	PA26268

Target gene [CDC42BPB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006044	chr14	14	7	6	27	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CDC42BPB expression and immune infiltrating cell level correlation result in HIV+ samples
CDC42BPB expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CDC42BPB expression and immune infiltrating cell level correlation result in HIV+ samples
CDC42BPB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).