HIV Target gene Detail Information

> CDC40 Gene Search Result

Gene Information

Gene Name	CDC40
Gene ID	51362
Gene Full Name	cell division cycle 40
Gene Alias	EHB3; PRP17; PRPF17
Transcripts	ENSG00000168438
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O60508
HGNC ID	HGNC:17350
VEGA ID	OTTHUMG00000015358
OMIM ID	605585
String ID	9606.ENSP00000357928
PharmGKB ID	PA134891332

Target gene [CDC40] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001717	chr6	131	1	5	137	View
4009591	chr6	6	5		11	View
4013725	chr6	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CDC40 expression and immune infiltrating cell level correlation result in HIV+ samples
CDC40 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CDC40 expression and immune infiltrating cell level correlation result in HIV+ samples
CDC40 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).