HIV Target gene Detail Information

> CDC34 Gene Search Result

Gene Information

Gene Name	CDC34
Gene ID	997
Gene Full Name	cell division cycle 34
Gene Alias	UBC3; UBCH3; UBE2R1; E2-CDC34
Transcripts	ENSG00000099804
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Nucleoplasm;Cytosol;
HPA Protein Class Info	Cancer-related genes, Enzymes, Predicted intracellular proteins
Uniport_ID	P49427
HGNC ID	HGNC:1734
VEGA ID	OTTHUMG00000180558
OMIM ID	116948
String ID	9606.ENSP00000215574
PharmGKB ID	PA26265

Target gene [CDC34] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003013	chr19	56	16		72	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CDC34 expression and immune infiltrating cell level correlation result in HIV+ samples
CDC34 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CDC34 expression and immune infiltrating cell level correlation result in HIV+ samples
CDC34 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).