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HBV Target gene Detail Information

> CDC27 Gene Search Result


Gene Information
Gene Name CDC27
Gene ID 996
Gene Full Name cell division cycle 27
Gene Alias APC3; HNUC; NUC2; H-NUC; ANAPC3; CDC27Hs; D0S1430E; D17S978E
Transcripts ENSG00000004897
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID P30260
HGNC ID HGNC:1728
VEGA ID OTTHUMG00000166429
OMIM ID 116946
String ID 9606.ENSP00000434614
PharmGKB ID PA26261
Target gene [CDC27] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000132 chr17 2453 1487 1917 5857 View
1002139 chr17 331 2 333 View
1011983 chr17 5 3 8 View
1403037 chr17 2453 1487 1917 5857 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of CDC27 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
CDC27 expression: Low -> High
Lollipop of CDC27 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of CDC27 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CDC27 expression and immune infiltrating cell level correlation result in HBV+ samples
CDC27 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).