HIV Target gene Detail Information

> CDC25C Gene Search Result

Gene Information

Gene Name	CDC25C
Gene ID	995
Gene Full Name	cell division cycle 25C
Gene Alias	CDC25; PPP1R60
Transcripts	ENSG00000158402
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
HPA Protein Class Info	Cancer-related genes, Enzymes, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	P30307
HGNC ID	HGNC:1727
VEGA ID	OTTHUMG00000129203
OMIM ID	157680
String ID	9606.ENSP00000321656
PharmGKB ID	PA100

Target gene [CDC25C] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4013013	chr5	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CDC25C expression and immune infiltrating cell level correlation result in HIV+ samples
CDC25C expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).