HIV Target gene Detail Information

> CDC14A Gene Search Result

Gene Information

Gene Name	CDC14A
Gene ID	8556
Gene Full Name	cell division cycle 14A
Gene Alias	cdc14; DFNB32; DFNB35; hCDC14; DFNB105
Transcripts	ENSG00000079335
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;Nuclear bodies;
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q9UNH5
HGNC ID	HGNC:1718
VEGA ID	OTTHUMG00000010987
OMIM ID	603504
String ID	9606.ENSP00000354916
PharmGKB ID	PA26254

Target gene [CDC14A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003949	chr1	41	8	3	52	View
4004261	chr1	27	14	6	47	View
4006436	chr1	19	6		25	View
4008472	chr1	14	1		15	View
4009122	chr1	1	10	1	12	View
4009508	chr1	1	9	1	11	View
4014064	chr1	1		1	2	View
4014299	chr1	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CDC14A expression and immune infiltrating cell level correlation result in HIV+ samples
CDC14A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CDC14A expression and immune infiltrating cell level correlation result in HIV+ samples
CDC14A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).