HIV Target gene Detail Information

> CD69 Gene Search Result

Gene Information

Gene Name	CD69
Gene ID	969
Gene Full Name	CD69 molecule
Gene Alias	AIM; EA1; MLR-3; CLEC2C; GP32/28; BL-AC/P26
Transcripts	ENSG00000110848
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	CD markers, Predicted membrane proteins
Uniport_ID	Q07108
HGNC ID	HGNC:1694
VEGA ID	OTTHUMG00000168481
OMIM ID	107273
String ID	9606.ENSP00000228434
PharmGKB ID	PA26233

Target gene [CD69] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005517	chr12	20	12		32	View
4010680	chr12	8			8	View
4011185	chr12	7			7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CD69 expression and immune infiltrating cell level correlation result in HIV+ samples
CD69 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CD69 expression and immune infiltrating cell level correlation result in HIV+ samples
CD69 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).