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HIV Target gene Detail Information

> CD6 Gene Search Result


Gene Information
Gene Name CD6
Gene ID 923
Gene Full Name CD6 molecule
Gene Alias TP120
Transcripts ENSG00000013725
Virus HIV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info CD markers, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID P30203
HGNC ID HGNC:1691
VEGA ID OTTHUMG00000167823
OMIM ID 186720
String ID 9606.ENSP00000323280
PharmGKB ID PA26230
Target gene [CD6] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4002413 chr11 15 43 37 95 View
4002469 chr11 35 20 38 93 View
4002893 chr11 71 5 76 View
4005718 chr5 19 8 3 30 View
4015227 chr11 1 1 View
4015588 chr11 1 1 View
4016570 chr11 0 View
4016571 chr11 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of CD6 expression and immune infiltrating cell level correlation result in HIV+ samples
CD6 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of CD6 expression and immune infiltrating cell level correlation result in HIV+ samples
CD6 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).