HIV Target gene Detail Information

> CD55 Gene Search Result

Gene Information

Gene Name	CD55
Gene ID	1604
Gene Full Name	CD55 molecule (Cromer blood group)
Gene Alias	CR; TC; DAF; CROM; CHAPLE
Transcripts	ENSG00000196352
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Blood group antigen proteins, CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID	P08174
HGNC ID	HGNC:2665
VEGA ID	OTTHUMG00000036255
OMIM ID	125240
String ID	9606.ENSP00000356030
Drugbank ID	BE0000929
PharmGKB ID	PA27137

Target gene [CD55] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009511	chr1	11			11	View
4011676	chr1	1	5		6	View
4012427	chr1		5		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CD55 expression and immune infiltrating cell level correlation result in HIV+ samples
CD55 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CD55 expression and immune infiltrating cell level correlation result in HIV+ samples
CD55 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).