HIV Target gene Detail Information

> CD48 Gene Search Result

Gene Information

Gene Name	CD48
Gene ID	962
Gene Full Name	CD48 molecule
Gene Alias	BCM1; BLAST; hCD48; mCD48; BLAST1; SLAMF2; MEM-102
Transcripts	ENSG00000117091
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Cytosol;Nucleoli fibrillar center;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P09326
HGNC ID	HGNC:1683
VEGA ID	OTTHUMG00000024009
OMIM ID	109530
String ID	9606.ENSP00000484431
PharmGKB ID	PA26223

Target gene [CD48] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002592	chr1	16	17	55	88	View
4012679	chr1	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CD48 expression and immune infiltrating cell level correlation result in HIV+ samples
CD48 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CD48 expression and immune infiltrating cell level correlation result in HIV+ samples
CD48 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).