HIV Target gene Detail Information

> CD3G Gene Search Result

Gene Information

Gene Name	CD3G
Gene ID	917
Gene Full Name	CD3g molecule
Gene Alias	T3G; IMD17; CD3-GAMMA
Transcripts	ENSG00000160654
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P09693
HGNC ID	HGNC:1675
VEGA ID	OTTHUMG00000166971
OMIM ID	186740
String ID	9606.ENSP00000431445
Drugbank ID	BE0003457
PharmGKB ID	PA26217

Target gene [CD3G] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4012205	chr11	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CD3G expression and immune infiltrating cell level correlation result in HIV+ samples
CD3G expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CD3G expression and immune infiltrating cell level correlation result in HIV+ samples
CD3G expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).