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HBV Target gene Detail Information

> CD2AP Gene Search Result


Gene Information
Gene Name CD2AP
Gene ID 23607
Gene Full Name CD2 associated protein
Gene Alias CMS
Transcripts ENSG00000198087
Virus HBV
Gene Type protein coding
HPA Location Info Plasma membrane;Centriolar satellite;Cytosol;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q9Y5K6
HGNC ID HGNC:14258
VEGA ID OTTHUMG00000014799
OMIM ID 604241
String ID 9606.ENSP00000352264
PharmGKB ID PA26208
Target gene [CD2AP] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009946 chr6 1 1 12 14 View
1013674 chr6 4 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of CD2AP expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
CD2AP expression: Low -> High
Lollipop of CD2AP expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of CD2AP expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CD2AP expression and immune infiltrating cell level correlation result in HBV+ samples
CD2AP expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).