HPV Target gene Detail Information

> CD274 Gene Search Result


Gene Information
Gene Name CD274
Gene ID 29126
Gene Full Name CD274 molecule
Gene Alias B7-H; B7H1; PDL1; PD-L1; PDCD1L1; PDCD1LG1
Transcripts ENSG00000120217
Virus HPV
Gene Type protein coding
HPA Location Info Actin filaments;Plasma membrane;Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, CD markers, FDA approved drug targets, Predicted membrane proteins
Uniport_ID Q9NZQ7
HGNC ID HGNC:17635
VEGA ID OTTHUMG00000019503
OMIM ID 605402
String ID 9606.ENSP00000370989
Drugbank ID BE0003441
PharmGKB ID PA134915280
FDA Approved Drug Atezolizumab;Avelumab;Durvalumab;Ipilimumab;Nivolumab;Pembrolizumab
Target gene [CD274] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5001151 chr9 15 33 48 View
5001750 chr9 18 4 2 24 View
5001857 chr9 15 4 2 21 View
5001859 chr9 15 4 2 21 View
5003058 chr9 5 1 6 View
5003214 chr9 5 5 View

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).