HIV Target gene Detail Information

> CD19 Gene Search Result

Gene Information

Gene Name	CD19
Gene ID	930
Gene Full Name	CD19 molecule
Gene Alias	B4; CVID3
Transcripts	ENSG00000177455
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins
Uniport_ID	P15391
HGNC ID	HGNC:1633
VEGA ID	OTTHUMG00000097049
OMIM ID	107265
String ID	9606.ENSP00000437940
Drugbank ID	BE0003496
PharmGKB ID	PA26192

Target gene [CD19] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000252	chr16	412	192	38	642	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CD19 expression and immune infiltrating cell level correlation result in HIV+ samples
CD19 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CD19 expression and immune infiltrating cell level correlation result in HIV+ samples
CD19 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).