HBV Target gene Detail Information

> CD109 Gene Search Result

Gene Information

Gene Name	CD109
Gene ID	135228
Gene Full Name	CD109 molecule
Gene Alias	p180; r150; CPAMD7
Transcripts	ENSG00000156535
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Cytosol;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	CD markers, Plasma proteins, Predicted membrane proteins
Uniport_ID	Q6YHK3
HGNC ID	HGNC:21685
VEGA ID	OTTHUMG00000015040
OMIM ID	608859
String ID	9606.ENSP00000287097
PharmGKB ID	PA134949237

Target gene [CD109] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006308	chr6	25	15		40	View
1015417	chr6		2		2	View
1015418	chr6		2		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CD109 expression and immune infiltrating cell level correlation result in HBV+ samples
CD109 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).