HTLV1 Target gene Detail Information

> CCT8 Gene Search Result

Gene Information

Gene Name	CCT8
Gene ID	10694
Gene Full Name	chaperonin containing TCP1 subunit 8
Gene Alias	Cctq; PRED71; D21S246; C21orf112
Transcripts	ENSG00000156261
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Intermediate filaments;Cytosol;Nucleoplasm;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	P50990
HGNC ID	HGNC:1623
VEGA ID	OTTHUMG00000044595
OMIM ID	617786
String ID	9606.ENSP00000286788
PharmGKB ID	PA26186

Target gene [CCT8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6015792	chr21	13			13	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of CCT8 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CCT8 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of CCT8 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CCT8 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of CCT8 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CCT8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).