HIV Target gene Detail Information

> CCR5 Gene Search Result

Gene Information

Gene Name	CCR5
Gene ID	1234
Gene Full Name	C-C motif chemokine receptor 5 (gene/pseudogene)
Gene Alias	CKR5; CCR-5; CD195; CKR-5; CCCKR5; CMKBR5; IDDM22; CC-CKR-5
Transcripts	ENSG00000160791
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins
Uniport_ID	P51681
HGNC ID	HGNC:1606
VEGA ID	OTTHUMG00000133481
OMIM ID	601373
String ID	9606.ENSP00000292303
Drugbank ID	BE0000911
PharmGKB ID	PA26170

Target gene [CCR5] related to virus gene/protein/region

ID	PMID	Mutation	Gene/Protein/Region	Description	Detail
1	25174000	Y435A	Gp120	C	View
2	25174000	M434A	Gp120	C	View
3	25174000	N197S	Gp120	C	View
4	25174000	L193A	Gp120	C	View
5	25174000	N188A	Gp120	C	View
6	25174000	N156A	Gp120	C	View
7	25174000	I154A	Gp120	C	View
8	25174000	R440E	Gp120	C	View
9	25174000	E168K	Gp120	C	View

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).