HIV Target gene Detail Information

> CCR3 Gene Search Result


Gene Information
Gene Name CCR3
Gene ID 1232
Gene Full Name C-C motif chemokine receptor 3
Gene Alias CKR3; CD193; CMKBR3; CC-CKR-3
Transcripts ENSG00000183625
Virus HIV
Gene Type protein coding
HPA Location Info Plasma membrane;
Membrane Info Predicted membrane proteins
HPA Protein Class Info CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID P51677
HGNC ID HGNC:1604
VEGA ID OTTHUMG00000133484
OMIM ID 601268
String ID 9606.ENSP00000441600
PharmGKB ID PA26168
Target gene [CCR3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001845 chr3 37 49 41 127 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of CCR3 expression and immune infiltrating cell level correlation result in HIV+ samples
CCR3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).