HIV Target gene Detail Information

> CCNT2 Gene Search Result


Gene Information
Gene Name CCNT2
Gene ID 905
Gene Full Name cyclin T2
Gene Alias CYCT2
Transcripts ENSG00000082258
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;Plasma membrane;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID O60583
HGNC ID HGNC:1600
VEGA ID OTTHUMG00000131712
OMIM ID 603862
String ID 9606.ENSP00000264157
PharmGKB ID PA26164
Target gene [CCNT2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4014426 chr2 1 1 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of CCNT2 expression and immune infiltrating cell level correlation result in HIV+ samples
CCNT2 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of CCNT2 expression and immune infiltrating cell level correlation result in HIV+ samples
CCNT2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).