HTLV1 Target gene Detail Information

> CCNO Gene Search Result

Gene Information

Gene Name	CCNO
Gene ID	10309
Gene Full Name	cyclin O
Gene Alias	CCNU; UDG2; CILD29
Transcripts	ENSG00000152669
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P22674
HGNC ID	HGNC:18576
VEGA ID	OTTHUMG00000162598
OMIM ID	607752
String ID	9606.ENSP00000282572
PharmGKB ID	PA38350

Target gene [CCNO] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000272	chr5	1984	349	113	2446	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of CCNO expression and immune infiltrating cell level correlation result in HTLV1+ samples
CCNO expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of CCNO expression and immune infiltrating cell level correlation result in HTLV1+ samples
CCNO expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).