HIV Target gene Detail Information

> CCND3 Gene Search Result


Gene Information
Gene Name CCND3
Gene ID 896
Gene Full Name cyclin D3
Transcripts ENSG00000112576
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Predicted intracellular proteins
Uniport_ID P30281
HGNC ID HGNC:1585
VEGA ID OTTHUMG00000014690
OMIM ID 123834
String ID 9606.ENSP00000362082
PharmGKB ID PA26152
Target gene [CCND3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001954 chr6 54 54 13 121 View
4004310 chr6 17 22 7 46 View
4006157 chr6 24 3 27 View
4011626 chr6 5 1 6 View
4015135 chr6 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of CCND3 expression and immune infiltrating cell level correlation result in HIV+ samples
CCND3 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of CCND3 expression and immune infiltrating cell level correlation result in HIV+ samples
CCND3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).