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HIV Target gene Detail Information

> CCDC88C Gene Search Result


Gene Information
Gene Name CCDC88C
Gene ID 440193
Gene Full Name coiled-coil domain containing 88C
Gene Alias HYC1; DAPLE; HKRP2; SCA40; KIAA1509
Transcripts ENSG00000015133
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoli fibrillar center;Nucleoplasm;
HPA Protein Class Info Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q9P219
HGNC ID HGNC:19967
VEGA ID OTTHUMG00000171099
OMIM ID 611204
String ID 9606.ENSP00000374507
PharmGKB ID PA162381879
Target gene [CCDC88C] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000328 chr14 22 356 156 534 View
4001687 chr14 49 31 60 140 View
4002262 chr14 66 31 5 102 View
4015613 chr14 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of CCDC88C expression and immune infiltrating cell level correlation result in HIV+ samples
CCDC88C expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of CCDC88C expression and immune infiltrating cell level correlation result in HIV+ samples
CCDC88C expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).