HTLV1 Target gene Detail Information

> CCDC28A Gene Search Result

Gene Information

Gene Name	CCDC28A
Gene ID	25901
Gene Full Name	coiled-coil domain containing 28A
Gene Alias	C6orf80; CCRL1AP
Transcripts	ENSG00000024862
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Plasma membrane;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q8IWP9
HGNC ID	HGNC:21098
VEGA ID	OTTHUMG00000015683
OMIM ID	615353
String ID	9606.ENSP00000479060
PharmGKB ID	PA134939277

Target gene [CCDC28A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000037	chr6	3655	2023	1703	7381	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of CCDC28A expression and immune infiltrating cell level correlation result in HTLV1+ samples
CCDC28A expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of CCDC28A expression and immune infiltrating cell level correlation result in HTLV1+ samples
CCDC28A expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of CCDC28A expression and immune infiltrating cell level correlation result in HTLV1+ samples
CCDC28A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).