HIV Target gene Detail Information

> CCDC25 Gene Search Result


Gene Information
Gene Name CCDC25
Gene ID 55246
Gene Full Name coiled-coil domain containing 25
Transcripts ENSG00000147419
Virus HIV
Gene Type protein coding
HPA Location Info Golgi apparatus;Nucleoplasm;Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q86WR0
HGNC ID HGNC:25591
VEGA ID OTTHUMG00000132173
OMIM ID 619100
String ID 9606.ENSP00000348933
PharmGKB ID PA142672183
Target gene [CCDC25] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001800 chr8 54 47 30 131 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of CCDC25 expression and immune infiltrating cell level correlation result in HIV+ samples
CCDC25 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of CCDC25 expression and immune infiltrating cell level correlation result in HIV+ samples
CCDC25 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).