HIV Target gene Detail Information

> CCDC18 Gene Search Result


Gene Information
Gene Name CCDC18
Gene ID 343099
Gene Full Name coiled-coil domain containing 18
Gene Alias NY-SAR-41
Transcripts ENSG00000122483
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q5T9S5
HGNC ID HGNC:30370
VEGA ID OTTHUMG00000010598
String ID 9606.ENSP00000383808
PharmGKB ID PA142672178
Target gene [CCDC18] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4008302 chr1 11 4 15 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of CCDC18 expression and immune infiltrating cell level correlation result in HIV+ samples
CCDC18 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of CCDC18 expression and immune infiltrating cell level correlation result in HIV+ samples
CCDC18 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).