HIV Target gene Detail Information

> CCDC15 Gene Search Result


Gene Information
Gene Name CCDC15
Gene ID 80071
Gene Full Name coiled-coil domain containing 15
Transcripts ENSG00000149548
Virus HIV
Gene Type protein coding
HPA Location Info Plasma membrane;Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q0P6D6
HGNC ID HGNC:25798
VEGA ID OTTHUMG00000165940
String ID 9606.ENSP00000341684
PharmGKB ID PA142672175
Target gene [CCDC15] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4003307 chr11 32 17 15 64 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of CCDC15 expression and immune infiltrating cell level correlation result in HIV+ samples
CCDC15 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of CCDC15 expression and immune infiltrating cell level correlation result in HIV+ samples
CCDC15 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).