HBV Target gene Detail Information

> CCDC146 Gene Search Result

Gene Information

Gene Name	CCDC146
Gene ID	57639
Gene Full Name	coiled-coil domain containing 146
Transcripts	ENSG00000135205
Virus	HBV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8IYE0
HGNC ID	HGNC:29296
VEGA ID	OTTHUMG00000162595
String ID	9606.ENSP00000285871
PharmGKB ID	PA162381475

Target gene [CCDC146] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004498	chr7	15	14	50	79	View
1005098	chr7	18	13	30	61	View
1005105	chr7	18	13	30	61	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CCDC146 expression and immune infiltrating cell level correlation result in HBV+ samples
CCDC146 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).