HTLV1 Target gene Detail Information

> CCDC141 Gene Search Result

Gene Information

Gene Name	CCDC141
Gene ID	285025
Gene Full Name	coiled-coil domain containing 141
Gene Alias	CAMDI
Transcripts	ENSG00000163492
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
HGNC ID	HGNC:26821
VEGA ID	OTTHUMG00000132578
OMIM ID	616031
String ID	9606.ENSP00000395995
PharmGKB ID	PA162381449

Target gene [CCDC141] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6004828	chr2	32	57	14	103	View
6009890	chr2	32	2		34	View
6026526	chr2		2		2	View
6028834	chr2		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of CCDC141 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CCDC141 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of CCDC141 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CCDC141 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).