HIV Target gene Detail Information

> CCAR2 Gene Search Result


Gene Information
Gene Name CCAR2
Gene ID 57805
Gene Full Name cell cycle and apoptosis regulator 2
Gene Alias DBC1; DBC-1; NET35; p30DBC; p30 DBC; KIAA1967
Transcripts ENSG00000158941
Virus HIV
Gene Type protein coding
HPA Location Info Nuclear bodies;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID Q8N163
HGNC ID HGNC:23360
OMIM ID 607359
String ID 9606.ENSP00000310670
PharmGKB ID PA134993792
Target gene [CCAR2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4011287 chr8 3 4 7 View
4013037 chr8 1 3 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of CCAR2 expression and immune infiltrating cell level correlation result in HIV+ samples
CCAR2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).