HIV Target gene Detail Information

> CC2D1A Gene Search Result

Gene Information

Gene Name	CC2D1A
Gene ID	54862
Gene Full Name	coiled-coil and C2 domain containing 1A
Gene Alias	MRT3; FREUD-1; Freud-1/Aki1
Transcripts	ENSG00000288293
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;Nucleoli fibrillar center;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q6P1N0
HGNC ID	HGNC:30237
VEGA ID	OTTHUMG00000181852
OMIM ID	610055
String ID	9606.ENSP00000313601
PharmGKB ID	PA142672197

Target gene [CC2D1A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009787	chr19	9	1		10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CC2D1A expression and immune infiltrating cell level correlation result in HIV+ samples
CC2D1A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CC2D1A expression and immune infiltrating cell level correlation result in HIV+ samples
CC2D1A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).