HIV Target gene Detail Information

> CBLL1 Gene Search Result


Gene Information
Gene Name CBLL1
Gene ID 79872
Gene Full Name Cbl proto-oncogene like 1
Gene Alias HAKAI; RNF188
Transcripts ENSG00000105879
Virus HIV
Gene Type protein coding
HPA Location Info Nuclear speckles;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Gene Function Oncogene
Uniport_ID Q75N03
HGNC ID HGNC:21225
VEGA ID OTTHUMG00000154809
OMIM ID 606872
String ID 9606.ENSP00000401277
PharmGKB ID PA134960329
Target gene [CBLL1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4015142 chr7 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of CBLL1 expression and immune infiltrating cell level correlation result in HIV+ samples
CBLL1 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of CBLL1 expression and immune infiltrating cell level correlation result in HIV+ samples
CBLL1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).