HIV Target gene Detail Information

> CBLB Gene Search Result

Gene Information

Gene Name	CBLB
Gene ID	868
Gene Full Name	Cbl proto-oncogene B
Gene Alias	Cbl-b; RNF56; Nbla00127
Transcripts	ENSG00000114423
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Enzymes, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q13191
HGNC ID	HGNC:1542
VEGA ID	OTTHUMG00000150654
OMIM ID	604491
String ID	9606.ENSP00000264122
PharmGKB ID	PA26116

Target gene [CBLB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003809	chr3	52	2		54	View
4010323	chr3	2	7		9	View
4012986	chr3		4		4	View
4013914	chr3		3		3	View
4015000	chr3		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CBLB expression and immune infiltrating cell level correlation result in HIV+ samples
CBLB expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CBLB expression and immune infiltrating cell level correlation result in HIV+ samples
CBLB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).