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HBV Target gene Detail Information

> CASR Gene Search Result


Gene Information
Gene Name CASR
Gene ID 846
Gene Full Name calcium sensing receptor
Gene Alias CAR; FHH; FIH; HHC; EIG8; HHC1; NSHPT; PCAR1; hCasR; GPRC2A; HYPOC1
Transcripts ENSG00000036828
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters
Uniport_ID P41180
HGNC ID HGNC:1514
VEGA ID OTTHUMG00000159491
OMIM ID 601199
String ID 9606.ENSP00000420194
Drugbank ID BE0000509
PharmGKB ID PA26097
FDA Approved Drug Parathyroid Hormone
Target gene [CASR] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1014938 chr3 1 2 3 View
1016157 chr3 1 1 View
1016158 chr3 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CASR expression and immune infiltrating cell level correlation result in HBV+ samples
CASR expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).