HIV Target gene Detail Information

> CASP8AP2 Gene Search Result


Gene Information
Gene Name CASP8AP2
Gene ID 9994
Gene Full Name caspase 8 associated protein 2
Gene Alias CED-4; FLASH; RIP25
Transcripts ENSG00000288475
Virus HIV
Gene Type protein coding
HPA Location Info Nuclear bodies;Nucleoli;
HPA Protein Class Info Predicted intracellular proteins
HGNC ID HGNC:1510
VEGA ID OTTHUMG00000015212
OMIM ID 606880
String ID 9606.ENSP00000478179
PharmGKB ID PA26093
Target gene [CASP8AP2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4006959 chr6 22 22 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of CASP8AP2 expression and immune infiltrating cell level correlation result in HIV+ samples
CASP8AP2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).