HBV Target gene Detail Information

> CASP10 Gene Search Result

Gene Information

Gene Name	CASP10
Gene ID	843
Gene Full Name	caspase 10
Gene Alias	MCH4; ALPS2; FLICE2
Transcripts	ENSG00000003400
Virus	HBV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Vesicles;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q92851
HGNC ID	HGNC:1500
VEGA ID	OTTHUMG00000132818
OMIM ID	601762
String ID	9606.ENSP00000286186
PharmGKB ID	PA26084

Target gene [CASP10] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001828	chr2	354	72	39	465	View
1400706	chr2	354	72	39	465	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CASP10 expression and immune infiltrating cell level correlation result in HBV+ samples
CASP10 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).