HIV Target gene Detail Information

> CASK Gene Search Result


Gene Information
Gene Name CASK
Gene ID 8573
Gene Full Name calcium/calmodulin dependent serine protein kinase
Gene Alias CMG; FGS4; LIN2; TNRC8; hCASK; CAGH39; CAMGUK; MICPCH; MRXSNA
Transcripts ENSG00000147044
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID O14936
HGNC ID HGNC:1497
VEGA ID OTTHUMG00000021378
OMIM ID 300172
String ID 9606.ENSP00000367408
Drugbank ID BE0002641
PharmGKB ID PA26081
Target gene [CASK] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4003327 chrX 10 51 3 64 View
4010525 chrX 7 1 8 View
4011299 chrX 6 1 7 View
4012143 chrX 2 3 5 View
4013760 chrX 3 3 View
4016784 chrX 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of CASK expression and immune infiltrating cell level correlation result in HIV+ samples
CASK expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of CASK expression and immune infiltrating cell level correlation result in HIV+ samples
CASK expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).