HIV Target gene Detail Information

> CASC3 Gene Search Result

Gene Information

Gene Name	CASC3
Gene ID	22794
Gene Full Name	CASC3, exon junction complex subunit
Gene Alias	BTZ; MLN51
Transcripts	ENSG00000108349
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear membrane;
HPA Protein Class Info	Cancer-related genes, Predicted intracellular proteins, Transporters
Uniport_ID	O15234
HGNC ID	HGNC:17040
VEGA ID	OTTHUMG00000133323
OMIM ID	606504
String ID	9606.ENSP00000264645
PharmGKB ID	PA134948596

Target gene [CASC3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009827	chr17	5	5		10	View
4009930	chr17	7	3		10	View
4010567	chr17	7	1		8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CASC3 expression and immune infiltrating cell level correlation result in HIV+ samples
CASC3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).