HPV Target gene Detail Information

> CARTPT Gene Search Result


Gene Information
Gene Name CARTPT
Gene ID 9607
Gene Full Name CART prepropeptide
Gene Alias CART
Transcripts ENSG00000164326
Virus HPV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info FDA approved drug targets, Predicted secreted proteins
Uniport_ID Q16568
HGNC ID HGNC:24323
VEGA ID OTTHUMG00000131261
OMIM ID 602606
String ID 9606.ENSP00000296777
Drugbank ID BE0000867
PharmGKB ID PA162381084
Target gene [CARTPT] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5403085 chr5 6 6 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of CARTPT expression and immune infiltrating cell level correlation result in HPV+ samples
CARTPT expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of CARTPT expression and immune infiltrating cell level correlation result in HPV+ samples
CARTPT expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of CARTPT expression and immune infiltrating cell level correlation result in HPV+ samples
CARTPT expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of CARTPT expression and immune infiltrating cell level correlation result in HPV+ samples
CARTPT expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of CARTPT expression and immune infiltrating cell level correlation result in HPV+ samples
CARTPT expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).