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HBV Target gene Detail Information

> CARM1 Gene Search Result


Gene Information
Gene Name CARM1
Gene ID 10498
Gene Full Name coactivator associated arginine methyltransferase 1
Gene Alias PRMT4
Transcripts ENSG00000142453
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Enzymes, Predicted intracellular proteins
Uniport_ID Q86X55
HGNC ID HGNC:23393
VEGA ID OTTHUMG00000180699
OMIM ID 603934
String ID 9606.ENSP00000325690
PharmGKB ID PA134959553
Target gene [CARM1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002703 chr19 173 26 20 219 View
1401807 chr19 173 26 20 219 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of CARM1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
CARM1 expression: Low -> High
Lollipop of CARM1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of CARM1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CARM1 expression and immune infiltrating cell level correlation result in HBV+ samples
CARM1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).