HIV Target gene Detail Information

> CARD16 Gene Search Result


Gene Information
Gene Name CARD16
Gene ID 114769
Gene Full Name caspase recruitment domain family member 16
Gene Alias COP; COP1; PSEUDO-ICE
Transcripts ENSG00000204397
Virus HIV
Gene Type protein coding
HPA Location Info Mitochondria;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q5EG05
HGNC ID HGNC:33701
VEGA ID OTTHUMG00000166157
OMIM ID 615680
String ID 9606.ENSP00000364858
PharmGKB ID PA164717628
Target gene [CARD16] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4006357 chr11 25 25 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of CARD16 expression and immune infiltrating cell level correlation result in HIV+ samples
CARD16 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of CARD16 expression and immune infiltrating cell level correlation result in HIV+ samples
CARD16 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).