HIV Target gene Detail Information

> CARD11 Gene Search Result

Gene Information

Gene Name	CARD11
Gene ID	84433
Gene Full Name	caspase recruitment domain family member 11
Gene Alias	PPBL; BENTA; BIMP3; IMD11; CARMA1; IMD11A
Transcripts	ENSG00000198286
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q9BXL7
HGNC ID	HGNC:16393
VEGA ID	OTTHUMG00000023023
OMIM ID	607210
String ID	9606.ENSP00000380150
PharmGKB ID	PA26073

Target gene [CARD11] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000663	chr7	211	90	26	327	View
4004901	chr7	23	15		38	View
4005294	chr7	34			34	View
4006941	chr7	10	6	6	22	View
4010639	chr7	5		3	8	View
4013493	chr7	2	1		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CARD11 expression and immune infiltrating cell level correlation result in HIV+ samples
CARD11 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CARD11 expression and immune infiltrating cell level correlation result in HIV+ samples
CARD11 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).