HIV Target gene Detail Information

> CAPZA1 Gene Search Result

Gene Information

Gene Name	CAPZA1
Gene ID	829
Gene Full Name	capping actin protein of muscle Z-line subunit alpha 1
Gene Alias	CAPZ; CAZ1; CAPPA1
Transcripts	ENSG00000116489
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	P52907
HGNC ID	HGNC:1488
VEGA ID	OTTHUMG00000011769
OMIM ID	601580
String ID	9606.ENSP00000263168
PharmGKB ID	PA26069

Target gene [CAPZA1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4010654	chr1	8			8	View
4011163	chr1	7			7	View
4012674	chr1	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CAPZA1 expression and immune infiltrating cell level correlation result in HIV+ samples
CAPZA1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CAPZA1 expression and immune infiltrating cell level correlation result in HIV+ samples
CAPZA1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).