HTLV1 Target gene Detail Information

> CAPN8 Gene Search Result


Gene Information
Gene Name CAPN8
Gene ID 388743
Gene Full Name calpain 8
Gene Alias nCL-2
Transcripts ENSG00000203697
Virus HTLV1
Gene Type protein coding
HPA Location Info Nuclear membrane;Nucleoplasm;Vesicles;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID A6NHC0
HGNC ID HGNC:1485
VEGA ID OTTHUMG00000037378
OMIM ID 618777
String ID 9606.ENSP00000355837
PharmGKB ID PA26065
Target gene [CAPN8] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6026133 chr1 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of CAPN8 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CAPN8 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).