HIV Target gene Detail Information

> CAPN1 Gene Search Result

Gene Information

Gene Name	CAPN1
Gene ID	823
Gene Full Name	calpain 1
Gene Alias	CANP; muCL; CANP1; SPG76; CANPL1; muCANP
Transcripts	ENSG00000014216
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID	P07384
HGNC ID	HGNC:1476
VEGA ID	OTTHUMG00000165614
OMIM ID	114220
String ID	9606.ENSP00000431984
Drugbank ID	BE0003346
PharmGKB ID	PA26057

Target gene [CAPN1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003616	chr11	56	2		58	View
4005553	chr11	18	7	6	31	View
4007338	chr11	17	3		20	View
4008514	chr11	7	8		15	View
4008596	chr11	6	8		14	View
4008755	chr11	6	8		14	View
4008870	chr11	7	6		13	View
4008914	chr11	7	6		13	View
4011436	chr11	4	2	1	7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CAPN1 expression and immune infiltrating cell level correlation result in HIV+ samples
CAPN1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CAPN1 expression and immune infiltrating cell level correlation result in HIV+ samples
CAPN1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).