HBV Target gene Detail Information

> CAP2 Gene Search Result

Gene Information

Gene Name	CAP2
Gene ID	10486
Gene Full Name	cyclase associated actin cytoskeleton regulatory protein 2
Transcripts	ENSG00000112186
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Plasma membrane;
HPA Protein Class Info	Cancer-related genes, Predicted intracellular proteins
Uniport_ID	P40123
HGNC ID	HGNC:20039
VEGA ID	OTTHUMG00000014311
OMIM ID	618385
String ID	9606.ENSP00000229922
PharmGKB ID	PA134989437

Target gene [CAP2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006511	chr3	37			37	View
1006512	chr3	37			37	View
1010326	chr6	10	2		12	View
1012477	chr3	6	1		7	View
1017385	chr3		1		1	View
1402977	chr6	10	2		12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CAP2 expression and immune infiltrating cell level correlation result in HBV+ samples
CAP2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).