HIV Target gene Detail Information

> CAP1 Gene Search Result

Gene Information

Gene Name	CAP1
Gene ID	10487
Gene Full Name	cyclase associated actin cytoskeleton regulatory protein 1
Gene Alias	CAP; CAP1-PEN
Transcripts	ENSG00000131236
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q01518
HGNC ID	HGNC:20040
VEGA ID	OTTHUMG00000004493
OMIM ID	617801
String ID	9606.ENSP00000361883
PharmGKB ID	PA399

Target gene [CAP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003784	chr12	53	1		54	View
4004252	chr1	15	31	1	47	View
4008400	chr12	14	1		15	View
4011344	chr1	6	1		7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CAP1 expression and immune infiltrating cell level correlation result in HIV+ samples
CAP1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CAP1 expression and immune infiltrating cell level correlation result in HIV+ samples
CAP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).